FIGURE 2.

The knockdown of AUF1 inhibited the proliferation, migration and invasion of colorectal cancer (CRC) cells. A, RNAi silencing of AUF1 in HCT116 and LoVo cells. β‐tubulin was used as a control. B, Cell counting kit‐8 assays demonstrated that the knockdown of AUF1 inhibited the cell proliferation of HCT116 and LoVo cells. C and D, Transwell assays demonstrated that the knockdown of AUF1 impeded the migration and invasion of HCT116 and LoVo cells. Relative numbers of migrating and invading cells are shown. E, The knockdown of AUF1 affected the expression of epithelial‐mesenchymal transition‐related proteins