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. 2020 Oct 31;32(5):547–563. doi: 10.21147/j.issn.1000-9604.2020.05.01

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Copyright © 2020 Chinese Journal of Cancer Research. All rights reserved.

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CNA and clinical association of SLC38A3 in ESCC integrated cohort and TCGA cohort. (A) CNA loss frequency of SLC38A3 in ESCC integrated cohort and TCGA cohort; (B) Scatter plot showed relative copy number variations of SLC38A3 in ESCC integrated cohort and TCGA cohort; (C) Correlation between SLC38A3 CNA and mRNA level in TCGA cohort (r=0.2909, P=0.004, Pearson Correlation Coefficient test); (D,E) Kaplan-Meier survival analysis of ESCC integrated cohort stratified by SLC38A3 CNA loss (n=314; P=0.011 for OS and P=0.014 for 5-year survival, log-rank test). CNA, copy number alteration; SLC38, solute carrier family 38; ESCC, esophageal squamous cell carcinoma; TCGA, The Cancer Genome Atlas; OS, overall survival.