S1. Frequencies of SLC38 family genetic alterations in integrated ESCC cohort in our data.
| Gene name | CNA frequency | Non-silent mutation frequency | |||||||
| Total | CNA gain | CNA loss | Frequency gain (%) | Frequency loss (%) | Total | Mutation | Frequency non-silent
mutation (%) |
||
| SLC38, solute carrier family 38; ESCC, esophageal squamous cell carcinoma; CNA, copy number alteration. | |||||||||
| SLC38A1 | 314 | 29 | 17 | 9.24 | 5.41 | 490 | 3 | 0.61 | |
| SLC38A2 | 314 | 27 | 15 | 8.60 | 4.78 | 490 | 3 | 0.61 | |
| SLC38A3 | 314 | 8 | 112 | 2.55 | 35.67 | 490 | 0 | 0 | |
| SLC38A4 | 314 | 21 | 21 | 6.69 | 6.69 | 490 | 1 | 0.20 | |
| SLC38A5 | 314 | 40 | 69 | 12.74 | 21.97 | 490 | 1 | 0.20 | |
| SLC38A6 | 314 | 60 | 38 | 19.11 | 12.10 | 490 | 3 | 0.61 | |
| SLC38A7 | 314 | 22 | 69 | 7.01 | 21.97 | 490 | 1 | 0.20 | |