4. Distribution of re-assessment risk level among all population after excluding participants received endoscopy (excluding esophageal cancer symptoms in questionnaire-based risk prediction model)*.

Risk group	Risk level	N	GC	NNS**	P	Sensitivity [% (95% CI)]	aHR (95% CI)
Adjusted for age group (40−49, 50−59, 60−69 years old), sex, ethnicity and marital status (never married, married, divorced and widow); *, Items, including dysphagia, esophageal reflux, hemoptysis, chronic heartburn, and current symptom of chest pain, were excluded. All population after excluding participants received endoscopy were re-stratified; **, The number of participants who should undergo endoscopy screening to identify one incident case; GC, gastric cancer; NNS, number needed to screen; 95% CI, 95% confidence interval; aHR, adjusted hazard ratio.
Low	0	35,616	19	1,269	<0.001	54.02% (43.04−64.64)	Reference
	1	15,139	21
High	≥2	27,874	47	593			1.90 (1.24−2.91)