S2. Multivariate Cox regression analyses of risk factors for PFS before PSM.

Variables	HR (95% CI)	P
PFS, progress-free survival; PSM, propensity score matching; T2DM, type 2 diabetes mellitus; HR, hazard ratio; 95% CI, 95% confidence interval.
T2DM (Yes vs. No)	1.396 (1.001−1.945 )	0.049
Ascites (Yes vs. No)	1.590 (1.233−2.050)	<0.001
Gastrectomy		0.148
Proximal vs. Total	0.845 (0.588−1.214)	0.362
Distal vs. Total	0.769 (0.586−1.008)	0.057
Lymphadenectomy (D2/D2+ vs. others)	0.522 (0.368−0.740)	<0.001
Radical resection (Yes vs. No)	0.473 (0.334−0.670)	<0.001
Grade		0.069
G3−4vs. G1−2	0.990 (0.813−1.204)	0.918
Unknown vs. G1−2	1.271 (0.979−1.649)	0.071
Vascular invasion (Yes vs. No)	1.078 (0.894−1.301)	0.431
Primary tumor invasion		0.001
T2 vs. T1	2.123 (1.316−3.424)	0.002
T3 vs. T1	2.720 (1.699−4.354)	<0.001
T4 vs. T1	3.332 (2.285−4.858)	<0.001
Lymph node status		<0.001
N1 vs. N0	1.667 (1.284−2.164)	<0.001
N2 vs. N0	2.434 (1.917−3.091)	<0.001
N3 vs. N0	3.669 (2.914−4.619)	<0.001
Metastasis (M1 vs. M0)	0.938 (0.642−1.371)	0.742
Tumor size (cm) (≥5 vs. <5)	0.834 (0.638−1.091)	0.072