Table 4.
Studies reporting influence of Deflazacort on development of scoliosis
| Study (ref no.) | Drug | No. patients | Scoliosis incidence/naïve | Scoliosis incidence treated |
|---|---|---|---|---|
| Alman Toronto8 | Deflazacort | 74 | 30/34 – 90% Age 18 min. |
4/40 – 10% Age 18 min. |
| Lebel Toronto25 | Deflazacort | 54 | 22/24 – 92% Mean age 22 (range 20 years–26 years) |
6/30 – 20% Mean age 22 (range 20 years–26 years) |
| Houde Montreal22 | Deflazacort | 79 | 28/42 had scoliosis with mean 46° | None <18° Mean age 13.1 |
| Singh Vancouver BC38 | Deflazacort | 37 | n/a | 1/49 ‘required’ scoliosis surgery |
| Wong Cincinatti42 | 90% Deflazacort 10% Prednisone |
n/a | 6/38 (16%) had scoliosis < 20% Age 13 years to 16 years |