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Selected tumor samples with rs78378222: (A–D) sequences chromatograms; (E) results of genotyping by PCR-RFLP method; (F) p.R196Q homo-zygote mutation. S1, 2, 4—tumor samples with C/C genotype rs78378222 (loss of heterozygosity in the TP53), S3—sample with A/C genotype rs78378222, M – 100 b.p. molecular weight marker.
