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. 2020 Jul 16;87(6):E680–E688. doi: 10.1093/neuros/nyaa301

TABLE.

EPZ-6438 Concentration in Serum, Normal Brain, and Brainstem Tumor

EPZ-6438 concentration (μg/mL)
Serum 12.78 ± 3.20
Normal brain 0.24 ± 0.22
Brainstem tumor 0.50 ± 0.27
EPZ-6438 brain penetration ratio (%)
Normal brain/serum 1.52 ± 1.16
Tumor/serum 3.74 ± 1.70