TABLE 3.
Quality of Life of Patients (N = 8) Before and After Treatment
| Baselinea | 6-mo follow-upb | 1-yr follow-up | |
|---|---|---|---|
| PDQ-8 | |||
| Total | 9.6 ± 5.4 | 4.1 ± 3.7a | 6.5 ± 4.5 |
| Mobility | 1.5 ± 0.9 | 1.0 ± 1.4 | 1.1 ± 1.1 |
| Activity of daily living | 1.5 ± 0.8 | 0.6 ± 1.1a | 0.8 ± 0.9 |
| Emotional well-being | 1.0 ± 1.1 | 0.3 ± 0.5 | 0.4 ± 0.7 |
| Stigma | 0.9 ± 1.1 | 0 ± 0 | 0.5 ± 0.8 |
| Social support | 0.6 ± 0.9 | 0 ± 0 | 0.8 ± 0.7b |
| Cognitions | 1.4 ± 1.1 | 0.3 ± 0.5 | 0.4 ± 0.7a |
| Communications | 1.0 ± 1.2 | 0.4 ± 1.1 | 1.8 ± 1.0a |
| Bodily discomfort | 1.8 ± 1.5 | 1.6 ± 1.0 | 0.9 ± 1.1 |
| EQ-5D-5L | |||
| Global health status | 72.5 ± 17.3 | 72.1 ± 20.4 | 83.1 ± 11.9 |
| Mobility | 1.0 ± 0.8 | 0.6 ± 0.5 | 0.6 ± 0.7 |
| Self-care | 1.3 ± 1.3 | 0.3 ± 0.5 | 0.4 ± 0.7a |
| Activities of daily living | 1.3 ± 1.6 | 0.6 ± 0.8 | 0.6 ± 0.9 |
| Pain or discomfort | 0.9 ± 0.8 | 0.4 ± 0.5 | 1.1 ± 1.0 |
| Anxiety or depression | 1.3 ± 1.0 | 0.1 ± 0.4a | 0.4 ± 0.5 |
| UPDRS-I | |||
| Total | 15.1 ± 7.6 | 8.9 ± 4.4a | 10.3 ± 6.9a |
| Mood status | 2.8 ± 3.1 | 0.4 ± 0.5a | 1.4 ± 1.3b |
| Other nonmotor functions | 12.4 ± 4.9 | 8.4 ± 4.2a | 8.9 ± 5.7a |
| UPDRS-II | |||
| Total | 16.4 ± 8.7 | 10.9 ± 5.1 | 10.5 ± 8.4a |
| Fine motor functions | 5.6 ± 4.1 | 5.6 ± 3.2 | 4.8 ± 4.0 |
| Tremor and eating task | 2.6 ± 1.8 | 1.0 ± 1.2a | 1.1 ± 1.4a |
| Complex motor functions | 8.1 ± 4.9 | 4.3 ± 2.9 | 4.6 ± 3.8a |
| BMI (kg/m²) | 26.9 ± 3.7 | n/a | 26.9 ± 3.8 |
BMI, body mass index; EQ-5D-5 L, 5-Level EuroQol-5 Dimensions; n/a, not applicable; PDQ, Parkinson Disease Questionnaire; UPDRS, Unified Parkinson Disease Rating Scale.
a,bThe letters a and b indicate a significant difference (P < .05) between 2 time points (Wilcoxon signed-ranks tests).
Values are presented as mean ± SD.