TABLE 4.
Nonmotor Symptoms of Patients (N = 8) Before and After Treatment
| Baselinea | 6-mo follow-upb | 1-yr follow-up | |
|---|---|---|---|
| NMSS | |||
| Total | 70/240 | 52/210 | 47/240 |
| Gastrointestinal tract (items 1-7 and 27) | 26/64 | 20/56 | 15/64a |
| Urinary tract (items 8-9) | 12/16 | 9/14 | 7/16 |
| Sexual function (items 18-19) | 6/16 | 2/14 | 0/16a |
| Cardiovascular (items 20-21) | 5/16 | 4/14 | 3/16 |
| Apathy/attention/memory (items 12, 13, and 15) | 8/24 | 7/21 | 10/24 |
| Hallucinations/delusions (items 14 and 30) | 1/16 | 2/14 | 0/16 |
| Depression/anxiety/anhedonia (items 16 and 17) | 6/16 | 3/14 | 6/16 |
| Pain (unrelated to other causes) (item 10) | 2/8 | 3/7 | 4/8 |
| Miscellaneous (items 11 and 29) | 4/16 | 2/14 | 2/16 |
| HADS | |||
| Total | 14.0 ± 8.3 | 11.4 ± 6.1 | 11.1 ± 7.1 |
| HADS-D | 7.4 ± 4.2 | 7.1 ± 4.2 | 6.4 ± 2.7 |
| HADS-A | 6.6 ± 4.7 | 3.3 ± 2.1 | 4.8 ± 5.0 |
| MMSE | 28.3 ± 2.2 | n/a | 28.1 ± 1.7 |
A, anxiety; D, depression; HADS, Hospital Anxiety and Depression Scale; MMSE, Mini-Mental State Examination. n/a, not applicable; NMSS, Non-Motor Symptoms Scale; one patient lost NMSS at 6-mo follow-up.
a,bThe letters a and b indicate a significant difference (P < .05) between 2 time points (Wilcoxon signed-ranks tests and Pearson's chi-square test).
Continuous variables are presented as mean (SD); categorical variables were summarized by counts of patients and ratios.