TABLE 1.
Characteristics of the prospective cohort studies included in the meta-analysis
| Author, year (ref) | Location | Study name | Gender | Age (mean), y | Follow-up, y | Cases, n | Participants, n | Participants with hypertension/diabetes/pre-existing stroke (%) |
|---|---|---|---|---|---|---|---|---|
| Al-Delaimy et al., 2004 (51) | USA | Nurses’ Health Study | F | 34–55 (44.5) | 18 | 1140 stroke cases | 83,272 | 15.4/2.0/0 |
| Bazzano et al., 2002 (24) | USA | NHANES I Epidemiologic Follow-up Study (NHEFS) | M/F | 25–74 (49) | 19 | 926 stroke cases | 9764 | 27/4.0/0 |
| Cui et al., 2010 (49) | Japan | Japan Collaborative Cohort Study | M/F | 40–79 (56) | 14 | 986 stroke cases | 58,730 | 19.6/4.5/0 |
| Dalmeijer et al., 2008 (26) | Dutch | Dutch PROSPECT-EPIC (European Prospective study Into Cancer and nutrition) cohort | F | 49–70 (57) | 8.1 | 227 CVA cases | 16,165 | 19.7/2.1/0 |
| He et al., 2004 (25) | USA | Health Professional Follow-up Study | M | 40–75 (52–55) | 14 | 725 stroke cases | 43,732 | 20.0/0/0 |
| Larsson et al., 20081 (47) | Finland | α-Tocopherol, β-carotene Cancer Prevention Study | M | 50–69 (57.1–58.1) | 13.6 | 2702 cerebral infarction cases; 383 intracerebral hemorrhage cases; 196 subarachnoid hemorrhage cases | 26,556 | N.A./6.3/0 |
| Luu et al., 2011 (50) | USA | Atherosclerosis Risk in Communities Study | M/F | 45–64 (54) | 16.5 | 594 stroke cases | 13,520 | 33.2/10.7/0 |
| Marniemi et al., 2005 (45) | Finland | Turku Health Survey | M/F | 65–99 (77) | 10 | 70 stroke cases | 755 | N.A./N.A./0 |
| Van Guelpen et al., 2005 (46) | Sweden | Northern Sweden Health and Disease Cohort | M/F | 25–74 (55.1) | 4.2 | 334 ischemic stroke cases; 62 hemorrhagic stroke cases | 1192 | 32.6/8.4/N.A. |
| Weng et al., 2008 (48) | China | Cardiovascular Disease risk Factor 2-township Study | M/F | 40–70 (56.6) | 10.6 | 132 stroke cases | 1772 | 23/10.0/0 |
| Zhao et al., 2019 (27) | China | Shanghai Men's Health Study, China | M | 40–74 (55.39) | 10.3 | 955 stroke cases | 59,746 | 29.4/6.0/3.8 |
| Zhao et al., 2019 (27) | China | Shanghai Women's Health Study, China | F | 40–70 (52.36) | 16.2 | 1317 stroke cases | 74,734 | 24.0/4.4/1.1 |