Table 3. Anti-FXa-IIa activities among different adherence groups in peak and trough concentration.
| Anti-FXa-IIa activities | MGLS | N | Mean | SD | 95% CI | P |
|---|---|---|---|---|---|---|
| Rivaroxaban anti-Xa-peak | High adherence | 107 | 269.1 | 12.2 | 244.8–293.3 | – |
| Intermediate adherence | 37 | 244.0 | 19.6 | 204.4–283.7 | – | |
| Total | 144 | 262.6 | 10.4 | 242.1–283.2 | 0.294 | |
| Rivaroxaban anti-Xa-trough | High adherence | 104 | 46.5 | 4.0 | 38.6–54.4 | – |
| Intermediate adherence | 31 | 45.2 | 5.7 | 33.5–56.9 | – | |
| Total | 135 | 46.2 | 3.3 | 39.6–52.8 | 0.870 | |
| Dabigatran anti-IIa-peak | High adherence | 76 | 156.9 | 14.3 | 128.5–185.4 | – |
| Intermediate adherence | 37 | 144.9 | 15.2 | 114.1–175.7 | – | |
| Low adherence | 6 | 188.4 | 79.9 | −17.1 to 394.0 | – | |
| Total | 119 | 154.8 | 10.9 | 133.2–176.4 | 0.688 | |
| Dabigatran anti-IIa-trough | High adherence | 74 | 70.2 | 6.9 | 56.5–83.9 | – |
| Intermediate adherence | 37 | 66.6 | 10.0 | 46.3–86.9 | – | |
| Low adherence | 6 | 70.1 | 33.7 | −16.5 to 156.7 | – | |
| Total | 117 | 69.0 | 5.6 | 58.0–80.0 | 0.957 |
Unit of anti-FXa-IIa activities: ng/mL. MGLS, Morisky, Green, and Levine Adherence Scale; CI, confidence interval; SD, standard deviation.