Table 3.
Micro-CT analysis.
| vBMD (mg/cm3) | BV/TV (%) | Tb.Th (mm) | Tb.Sp (mm) | Tb.N (mm−1) | Tb.Pf (mm−1) | |||
|---|---|---|---|---|---|---|---|---|
| Osteoarthritis joints (OA) | SHAM | LFC | 695.43 ± 116.60 | 62.37 ± 4.56 | 0.16 ± 0.02 | 0.10 ± 0.01 | 3.89 ± 0.24 | 3.03 ± 1.46 |
| MFC | 708.81 ± 95.65 | 63.62 ± 3.52 | 0.16 ± 0.02 | 0.10 ± 0.02 | 3.94 ± 0.34 | 1.92 ± 2.97 | ||
| LTP | 735.11 ± 106.36 | 61.92 ± 13.99 | 0.14 ± 0.04 | 0.10 ± 0.03 | 4.61 ± 0.42 | −0.86 ± 4.89 | ||
| MTP | 709.86 ± 98.55 | 59.20 ± 12.84 | 0.15 ± 0.04 | 0.11± 0.04 | 4.08 ± 0.71 | 3.66 ± 4.73 | ||
| CONT | LFC | 452.39 ± 158.99a | 50.17 ± 8.59a | 0.14 ± 0.02 | 0.15 ± 0.06 | 3.60 ± 0.46 | 5.44 ± 2.22 | |
| MFC | 546.15 ± 134.36a | 55.94 ± 6.50a | 0.15 ± 0.02 | 0.13 ± 0.04 | 3.75 ± 0.39 | 3.89 ± 2.98 | ||
| LTP | 487.01 ± 108.37a | 52.67 ± 6.46 | 0.12 ± 0.02 | 0.12 ± 0.03 | 4.29 ± 0.55 | 3.39 ± 2.57 | ||
| MTP | 537.37 ± 109.40a | 55.81 ± 6.01 | 0.14 ± 0.02 | 0.14 ± 0.06 | 3.97 ± 0.60 | 3.64 ± 3.15 | ||
| RIS | LFC | 457.84 ± 170.76a | 50.40 ± 10.02a | 0.16 ± 0.02 | 0.18 ± 0.05a | 3.22 ± 0.43a | 3.81 ± 4.58 | |
| MFC | 456.73 ± 125.69a | 50.31 ± 6.47a | 0.16 ± 0.02 | 0.18 ± 0.04a | 3.23 ± 0.32a,b | 3.81 ± 2.63 | ||
| LTP | 449.35 ± 226.52a | 53.23 ± 9.64 | 0.14 ± 0.03 | 0.14 ± 0.04a | 3.84 ± 0.50a | 2.15 ± 3.74 | ||
| MTP | 446.98 ± 129.22a | 47.80 ± 9.30a | 0.15 ± 0.34 | 0.21 ± 0.08a | 3.22 ± 0.59a | 4.47 ± 3.57 | ||
| Healthy joints (HT) | SHAM | LFC | 821.91 ± 74.53 | 67.07 ± 2.54 | 0.17 ± 0.01 | 0.08 ± 0.01 | 3.85 ± 0.18 | 2.52 ± 1.35 |
| MFC | 861.11 ± 58.66 | 69.84 ± 1.55 | 0.18 ± 0.01 | 0.08 ± 0.01 | 3.94 ± 0.14 | −0.69 ± 1.41 | ||
| LTP | 758.38 ± 185.16 | 69.23 ± 8.73 | 0.15 ± 0.03 | 0.08 ± 0.02 | 4.72 ± 0.80 | −4.48 ±7.01 | ||
| MTP | 813.52 ± 82.51 | 63.30 ± 10.88 | 0.15 ± 0.04 | 0.09 ± 0.04 | 4.28 ± 0.85 | 0.29 ± 5.16 | ||
| CONT | LFC | 773.16 ± 86.54 | 65.98 ± 3.34 | 0.17 ± 0.02 | 0.09 ± 0.02 | 3.84 ± 0.39 | 1.26 ± 1.71 | |
| MFC | 806.95 ± 101.34 | 67.77 ± 4.36 | 0.18 ± 0.02 | 0.10 ± 0.01 | 3.73 ± 0.38 | 0.46 ± 2.44 | ||
| LTP | 758.40 ± 227.16 | 59.06 ± 18.72 | 0.14 ± 0.05 | 0.11 ± 0.05 | 4.41 ± 0.44 | −0.66 ± 7.21 | ||
| MTP | 666.73 ± 231.44 | 53.37 ± 16.43 | 0.15 ± 0.06 | 0.15 ± 0.07 | 3.82 ± 0.61 | 3.75 ± 6.29 | ||
| RIS | LFC | 758.16 ± 66.75 | 64.04 ± 3.09 | 0.19 ± 0.01 | 0.11 ± 0.01a | 3.33 ± 0.20a,b | 4.45 ± 2.47b | |
| MFC | 749.07 ± 94.66 | 64.11 ± 4.34 | 0.19 ± 0.01 | 0.11 ± 0.02a,b | 3.39 ± 0.26a | 3.54 ± 3.34a | ||
| LTP | 733.36 ± 171.25 | 61.67 ± 14.99 | 0.16 ± 0.05 | 0.12 ± 0.06a | 4.02 ± 0.39a | −1.00 ± 3.40 | ||
| MTP | 688.92 ± 87.87 | 54.36 ± 12.42 | 0.17 ± 0.05 | 0.17 ± 0.09 | 3.44± 0.77 | 4.16 ± 6.43 |
Micro-CT results: vBMD, volumetric bone mineral density; BV/TV, bone volume fraccion; Tb.Th, trabecular thickness; Tb:Sp, trabecular separation; Tb:N, trabecular number; Tb.Pf, trabecular pattern factor. Values represent the mean and SD. Statistical significant differences are marked in “bold text.” p < 0.05:
a
vs. SHAM,
b
vs. CONT.