TABLE 1.

Genes encoding metal transporters implicated in survival in calprotectin

Locus tag	Name	Description	P value control vs. calprotectin at:
			Subinhibitory dose	Inhibitory dose
SAK_0218	adcC	Zinc ABC transporter, ATP-binding protein	0.01132	0.00004049
SAK_0252	SAK_0252	Peptide/opine/nickel uptake ABC transporter, substrate-binding protein	2.713E–15	1.019E–15
SAK_0253	SAK_0253	Peptide/opine/nickel uptake ABC transporter, permease protein	2.396E–19	4.972E–11
SAK_0254	SAK_0254	Peptide/opine/nickel uptake ABC transporter, permease protein	1.971E–17	1.16E−20
SAK_0255	SAK_0255	Peptide/opine/nickel uptake ABC transporter, ATP-binding protein	3.388E–19	7.2E–19
SAK_0514	czcD	Cation efflux transporter, cation diffusion facilitator (CDF) family	0.002825	0.01577
SAK_0515	scZA	Transcriptional regulator, TetR family	3.515E–07	0.00000315
SAK_0516	SAK_0516	Transcriptional regulator, AraC family	7.831E–11	6.017E–10
SAK_0685	adcA	Zinc ABC transporter, zinc-binding protein	2.612E−28	2.018E−21
SAK_0871	mntH	Mn2+/Fe2+ transporter, NRAMP family	0.006823	0.04543
SAK_1539	nikE	Nickel ABC transporter, ATP-binding protein	0.04795
SAK_1554	mtsC	Metal ABC transporter, permease protein	9.914E−12
SAK_1555	mtsB	Metal ABC transporter, ATP-binding protein	2.325E−10
SAK_1556	mtsA	Metal ABC transporter, metal-binding lipoprotein	1.381E−11	0.003134
SAK_1897	shtII	Streptococcal histidine triad family protein	0.0001926	2.972E−08
SAK_1898	adcAII	Laminin-binding surface protein		0.04445
SAK_2051	cadD	Cadmium resistance protein	0.000001093	6.657E−11