Table 4. Univariable analysis of clinical and indocyanine green angiographic variables for nipple-areola complex necrosis.
| Variables | Unadjusted OR (95% CI) | P |
|---|---|---|
| Age | 1.068 (0.980–1.164) | 0.132 |
| BMI | 0.973 (0.749–1.264) | 0.836 |
| Hypertension | 1.306 (0.130–13.080) | 0.821 |
| Diabetes | 2.722 (0.223–33.279) | 0.433 |
| Smoking history | NA† | NA† |
| Previous chemotherapy | 0.597 (0.066–5.387) | 0.646 |
| Incision type | ||
| Conventional lateral radial incisions | Ref. | Ref. |
| Pure hemi-periareolar incision | 5.344 (0.627–45.535) | 0.125 |
| Mastectomy weight | 1.002 (0.997–1.006) | 0.515 |
| Implant volume | 1.001 (0.995–1.008) | 0.682 |
| Implant position | ||
| Prepectoral | Ref. | Ref. |
| Subpectoral | 1.687 (0.425–6.704) | 0.457 |
| Sternal notch to nipple distance‡ | 1.010 (0.762–1.339) | 0.946 |
| Surgery duration ± SD, min | ||
| Axillary lymph node management | ||
| None | Ref. | Ref. |
| SLNB | 0.656 (0.059–7.280 | 0.732 |
| ALND | 0.375 (0.025–5.572) | 0.476 |
| Duration of drain insertion ± SD, day | 1.011 (0.798–1.282) | 0.925 |
| Nipple perfusion time | 1.027 (1.013–1.042) | <0.001* |
| Nipple perfusion pattern | ||
| Perfusion (including rapid and delayed perfusion) | Ref. | Ref. |
| No perfusion | 5.236 (2.244–12.217) | <0.001* |
OR, odds ratio; CI, confidence interval; BMI, body mass index; SD, standard deviation; SLNB, sentinel lymph node biopsy; ALND, axillary lymph node dissection. *Statistically significant; †Not available according to the lack of events in the nipple-areola complex necrosis group; ‡Sternal notch to nipple distance was measured using Crisalix 3D Surface Imager (Crisalix, S.A., Lausanne, Switzerland).