Table 1. Discrepant comments by three reviewers from two thyroid journals on an encapsulated papillary patterned thyroid tumor reported by Ohba et al. (21).
Reviewer | Comments by reviewers | Diagnosis |
---|---|---|
Reviewer 1 | The micrographs show a lesion with blunt papilla lacking nuclear features of PTC typically characterized as papillary hyperplasia | Benign: FA with papillary hyperplasia |
Reviewer 2 | In the past, a case such as this one would have been called PTC. However, in current times, the issue of encapsulation and the demonstration of nuclear features have become very important. I am not opposed to the introduction of the NEPRAS terminology. Time will tell if more cases are reported and whether it will catch | Borderline |
Reviewer 3 | The images show undoubted papillae with nuclear features which would be interpreted by most pathologists as those of PTC, therefore as the lesion is encapsulated it would be reasonable to diagnose this as an encapsulated follicular variant of PTC | Malignant: PTC |
PTC, papillary thyroid carcinoma; FA, follicular adenoma.