Table 3. Clinicopathological variables for 5-year disease-free, locoregional recurrence-free, distant metastasis-free, and overall survival in the univariate analysis.
Variables | Disease-free survival | Overall survival | |||
---|---|---|---|---|---|
χ2 | P value | χ2 | P value | ||
Quadrant (outer vs. upper-inner vs. lower-inner/central) | 6.345 | 0.012 | 3.924 | 0.048 | |
Histological grade (I vs. II vs. III) | 27.8752 | <0.001 | 57.655 | <0.001 | |
pCR (yes vs. no) | 0.234 | 0.629 | 2.540 | 0.111 | |
Type of surgery (MRM vs. BCS) | 0.0077 | 0.9301 | 0.4431 | 0.5056 | |
Clinical stage (II vs. III) | 64.2814 | <0.001 | 4.810 | 0.028 | |
IMN-RT (yes vs. no) | 0.616 | 0.433 | 0.0002 | 0.9876 | |
Standard endocrine therapy (yes vs. no) | 1.246 | 0.264 | 0.267 | 0.606 | |
Luminal subtype (luminal A vs. luminal B) | 7.039 | 0.008 | 13.838 | <0.001 | |
Pretreatment LMR (>5.2 vs. ≤5.2) | 27.758 | <0.001 | 16.531 | <0.001 | |
Margin (negative vs. positive) | 0.0974 | 0.7549 | 0.0704 | 0.7908 | |
ypN0 (yes vs. no) | 1.108 | 0.292 | 4.637 | 0.031 | |
PR (negative vs. positive) | 0.954 | 0.329 | 2.104 | 0.147 | |
RT (yes vs. no) | 0.298 | 0.585 | 1.136 | 0.286 | |
NAC regimen (TC vs. AT) | 1.671 | 0.196 | 0.117 | 0.732 | |
Pathological stage (I–II vs. III) | 1.542 | 0.214 | 3.272 | 0.070 |
AT, doxorubicin docetaxel; BCS, breast-conserving surgery; IMN-RT, internal mammary node radiotherapy; LMR, lymphocyte-to-monocyte ratio; MRM, modified radical mastectomy, NAC, neoadjuvant chemotherapy; pCR, pathological complete response; PR, progesterone receptor; RT, Radiation Therapy; TC, docetaxel cyclophosphamide; ypN0, N0 after neoadjuvant chemotherapy.