Table 2. Bivariate and multivariate logistic regression analysis for clinical significance of VE1 expression.

Variable	Bivariate analysis, crude OR (P value)	Multivariate analysis, adjusted OR (P value)
Age
<55	Reference
≥55	1.403 (0.096)	1.147 (0.564)
Sex
Female	Reference
Male	1.133 (0.594)
Histological variant
1. Classic	15.305 (<0.001)	27.631 (0.002)
2. Encapsulated	2.600 (0.321)	6.103 (0.134)
3. Follicular	1.327 (0.735)	2.672 (0.372)
4. Diffuse sclerosing	4.333 (0.217)	9.964 (0.100)
5. Tall cell	84.50 (0.001)	107.675 (0.002)
6. Other†	Reference
Margin
Negative	Reference
Positive	1.649 (0.035)	0.970 (0.915)
Extrathyroidal extension
Absent	Reference
Present	2.763 (<0.001)	2.026 (0.004)
Hashimoto’s thyroiditis
Absent	Reference
Present	0.340 (0.012)	0.390 (0.045)

^†, includes columnar cell variant, cribriform-morular variant, solid variant, oncocytic variant, and Warthin-like variant.