Table 5. BSRTC diagnoses, diagnostic features, and molecular testing guidelines (16).
| BSRTC diagnosis | Diagnostic features | Molecular testing |
|---|---|---|
| Nondiagnostic/Unsatisfactory | Insufficient amount of diagnostic elements | No |
| Benign | Benign follicular nodule | No |
| Lymphocytic thyroiditis | ||
| Granulomatous thyroiditis | ||
| Other | ||
| AUS/FLUS | Architectural atypia | Yes |
| Cytologic atypia | ||
| Architectural and cytologic atypia | ||
| FN/SFN | Cellular specimen with crowding and/or microfollicle formation and with or without mild nuclear atypia | Yes |
| Hürthle cell type | ||
| SM | Overt cytologic atypia but missing one or two key diagnostic features | Veracyte Afirma GSC, No |
| ThyroSeq v3, Yes | ||
| Malignant | Malignant cytologic criteria fulfilled | No |