Table 6. Diagnostic efficacy results.

Classification standard	AUC	P	Sensitivity	Specificity	PPV	NPV	Accuracy
Old TI-RADS	0.646	0.030	40.00	88.57	80.00	56.36	62.67
New TI-RADS by CDFI	0.690	0.005	37.50	88.57	78.95	55.36	61.33
New TI-RADS by SMI	0.840	0.000	65.00	85.71	83.87	85.71	74.67
New TI-RADS by CEUS	0.910	0.000	82.50	91.43	91.67	82.05	86.67
New TI-RADS by CEUS+SMI	0.903	0.000	92.5	80.00	84.09	90.32	86.67

AUC, area under the curve; TI-RADS, Thyroid Imaging Reporting and Data System; CDFI, color Doppler imaging; SMI, superb micro-vascular imaging; CEUS, contrast-enhanced ultrasound.