Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Nov 2;11:536854. doi: 10.3389/fgene.2020.536854

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2020 Hu, Che, Yang, Xie and Tian.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

shRNA-mediated silencing of HDAC3 alleviates DM-induced PBMC apoptosis in vivo. (A) Glucose level of rats. (B) Insulin levels of rats. (C) miR-296-5p expression in PBMCs of rats determined by RT-qPCR. (D) Quantitative analysis of PBMC apoptosis identified by flow cytometric analysis. (E) The expression of HDAC3, BCL-XL, and C-caspase-3 in PBMCs normalized to GAPDH determined by Western blot analysis. ^*p < 0.05 compared with sham-operated rats, ^#p < 0.05 compared with rats with DM. Data comparisons among multiple groups were performed using one-way analysis of variance. n = 8.