Table 3.
Values of the best radiomics features (Rad) and the conventional CMR indices (Conv).
| CV risk factor | Single most defining feature | CV risk cohort | Healthy cohort | ACC | ||
|---|---|---|---|---|---|---|
| Mean | SD | Mean | SD | |||
| High cholesterol | Rad: Spherical disproportion MYO ED (S) | 3.631 | 0.290 | 3.779 | 0.311 | 0.611 |
| Conv: LVM (g) | 93.493 | 24.199 | 85.667 | 24.104 | 0.576 | |
| Diabetes | Rad: Median MYO ES (F) | 67.887 | 9.058 | 74.652 | 10.514 | 0.658 |
| Conv: LVM (g) | 97.856 | 24.250 | 85.931 | 25.024 | 0.605 | |
| Hypertension | Rad: Surface area to volume ratio MYO ED (S) | 0.390 | 0.054 | 0.425 | 0.06 | 0.618 |
| Conv: LVM (g) | 97.131 | 25.849 | 85.623 | 24.101 | 0.593 | |
| Current smokers | Rad: Gray level non uniformity MYO ES (T) | 573.448 | 134.355 | 515.789 | 140.307 | 0.609 |
| Conv: LVM (g) | 93.614 | 24.804 | 84.549 | 25.426 | 0.564 | |
| Previous smokers | Rad: Surface area to volume ratio MYO ED (S) | 0.405 | 0.058 | 0.425 | 0.062 | 0.574 |
| Conv: LVM (g) | 91.902 | 24.896 | 85.623 | 24.101 | 0.552 | |
Feature values from risk groups and healthy individuals were statistically significantly different for all selected features (Bonferroni adjusted p-value < 0.05/684). S, shape; F, first-order; T, texture; SD, standard deviation; ACC, accuracy; CV, cardiovascular; MYO, LV myocardium; ED/ES, end-diastole/systole; LVM, left ventricular mass (in grams; g).