TABLE 5.

Main changes adopted in the model of Farhat et al. (2017) and the main result.

Main changes	Main result
- Uncommitted osteoblast differentiation into preosteoblasts is governed by each of TGFβ and Wnt. - Active osteoclasts’ apoptosis varied from a base rate noted αoca1, and then, it follows TGFβ ’s concentration. - Bone formation is controlled by calcium concentration and not only by bone cell activity.	There are two levels of osteogenic states, the low, which depends on TGFβ activation by prostate cancer cells, and the high, which is related to the Wnt existence.

Wnt, wingless-int.