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. 2020 Nov 10;16:1081–1088. doi: 10.2147/TCRM.S269161

Table 4.

Subgroup Analysis of Clinical Manifestations Between Patients Who Survived and Those Who Died

Clinical Manifestations Survived
(n = 158)
Died
(n = 5)
p-value*
Number (%) male to female 88:70 (55.7:44.3) 3:2 (60:40) 1.00
Age in years, mean ± SD (min-max) 40.7 ± 22.1(2–86) 60 ± 16.9(47–88) 0.056
Number (%) of age in years 0.496
 Less than 5 years 18(11.4) 0
 6–12 years 2 (1.3) 0
 13–19 years 7 (4.4) 0
 20–39 years 43(27.2) 0
 40–59 years 54(34.2) 3 (60)
 More than 60 years 34 (21.5) 2 (40)
Time to hospital in hours, median (min-max); data available for 160 patients 1 (0.17–72)
n = 156
4 (1–8)
n = 4
0.064
Estimated ingestion amount in grams, median (min-max); data available for 68 patients 2.5 (0.1–30)
n = 65
40 (14–87.5)
n = 3
0.004**
Number (%) of initial signs and symptomsa
 Gastrointestinal: 98 (62.0) 2 (40) 0.376
  Nausea/vomiting 84 (53.2) 2 (40) 0.668
  Abdominal pain 33 (20.9) 0 0.584
  Burning sensation in    throat 11 (7.0) 1 (20) 0.321
 Cardiovascular: 13 (8.2) 3 (60) 0.007**
  Tachycardia 3 (1.9) 3 (60) <0.001**
  Bradycardia 1 (0.6) 0 (0) 1.000
  Hypertension 8 (5.1) 1 (20) 0.250
  Hypotension 2 (1.3) 1 (20) 0.090
  Cardiac arrest 0 1 (20) 0.031**
 Central nervous system: 5 (3.2) 3 (60) 0.001**
  Dizziness 20 (12.7) 1 (20) 0.503
  Drowsiness 5 (3.2) 1 (20) 0.173
  Headache 4 (2.5) 0 1.000
  Coma 0 1 (20) 0.031**
 Respiratory:
  Dyspnea 0 2 (40) 0.001**
 Other:
  Muscle twitchingb 2 (1.3) 0 1.000
  Diaphoresis 4 (2.5) 2 (40) 0.011**
  Salivation 6 (3.8) 0 (0) 1.000
  Paresthesiab 3 (1.9) 0 (0) 1.000

Notes: aData from all routes of exposure. bSymptoms occurred only after dermal or inhalational exposures. * Comparisons between-group were performed by Student’s t-test if the data were normally distributed and by the Mann–Whitney U-test if they were not normally distributed. Differences in categorical variables were evaluated by chi-squared analysis and Fisher’s exact test. ** Statistically significant.