Table 2.
Phenotypes of E13.5 embryos from intercrosses of Pdgfrafl/fl;Pdgfrbfl/fl mice with Pdgfra+/fl;Pdgfrb+/fl;Wnt1-Cre+/Tg mice.
| Genotype | Expected | Observed | Normal | Dead | Facial cleft | Facial bleb | Facial hemorrhage |
|---|---|---|---|---|---|---|---|
| α+/fl;β+/fl;W1C+/+ | 0.125 | 0.077 | 5/5 | 3 | 0/5 | 0/5 | 0/5 |
| α+/fl;β+/fl;W1C+/Tg | 0.125 | 0.173 | 5/16 | 2 | 0/16 | 10/16 | 2/16 |
| α+/fl;βfl/fl;W1C+/+ | 0.125 | 0.135 | 12/13 | 1 | 0/13 | 1/13 | 0/13 |
| α+/fl;βfl/fl;W1C+/Tg | 0.125 | 0.154 | 2/13 | 3 | 0/13 | 11/13 | 9/13 |
| αfl/fl;β+/fl;W1C+/+ | 0.125 | 0.125 | 2/12 | 1 | 0/12 | 10/12 | 2/12 |
| αfl/fl;β+/fl;W1C+/Tg | 0.125 | 0.115 | 0/12 | 0 | 12/12 | 12/12 | 9/12 |
| αfl/fl;βfl/fl;W1C+/+ | 0.125 | 0.144 | 5/14 | 1 | 0/14 | 9/14 | 2/14 |
| αfl/fl;βfl/fl;W1C+/Tg | 0.125 | 0.077 | 0/8 | 0 | 8/8 | 7/8 | 8/8 |