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. 2020 Nov 2;11:583478. doi: 10.3389/fphys.2020.583478

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Copyright © 2020 Zeng, Liang, Wu, Zhang, Lv and Chen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Exrcise interventions increased the cross-sectional area (CSA) of skeletal muscle fibers in aged rats. (A) Morphological changes of skeletal muscle were observed with HE staining (scale bar, 50 μm). (B) The CSA of skeletal muscle fibers in aged rats was measured from the selected 150 gastrocnemius muscle fibers. ^**p < 0.01 vs. YC group; ^#p < 0.05 and ^##p < 0.01 vs. OC group. All data are presented as mean ± standard deviation (M ± SD) from the selected 150 gastrocnemius muscle fibers in each group (n = 150).