Table 3.
Clinical outcomes and costs per intervention by resource use.
| Conventional OR | LF-iMR | LF-iMR- Conventional OR) | p-value | ||
|---|---|---|---|---|---|
| Clinical outcomes | |||||
| Gross Total Resection (%)a | 56.2 | 70.0 | 13.8 | 0.121 | |
| Complications (%)b | 21.3 | 14.0 | −7.3 | 0.639 | |
| Postoperative KPS* | 77 +/− 18 | 84 +/− 8 | 7 | 0.000 | |
| Range | 60–100 | 60–100 | |||
| 1-year OS (%) | 84.3 | 88 | 3.7 | 0.874 | |
| 2-years OS (%) | 73.3 | 70 | −3.3 | 0.744 | |
| R-KPS (%)c,* | 35 | 52 | 17 | 0.039 | |
| 1-year PFS (days) | 295 | 333 | 38 | 0.025 | |
| Costs per intervention | |||||
| Operating Room | 3,356 € | 5,162 | 1,806 | 0.0000 | |
| ICU | 717 € | 472 € | −245 € | 0.0375 | |
| Diagnostic images | 1,269 € | 1,082 € | −186 € | 0.0473 | |
| Hospitalization | 5,087 € | 4,177 € | −910 € | 0.0332 | |
ICU, Intensive Care Unit; KPS, Karnofsky performance status; OS, overall survival; PFS, Progression-free survival; R-KPS, Resection and postoperative KPS.
*Effectiveness measures considered in the cost-effectiveness analysis.
aPercentage of patients.
bPercentage of patients who suffered one or more complications.
cPercentage of patients presenting with a Subtotal or Gross total resection and an equal or higher postoperative KPS.