Table 3.
Incidence of common and uncommon EGFR mutation in Xuanwei region.
| Xuanwei | META | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Yes | No | Total | Rate | Rate | 95%CI | ||||
| Common mutation | Guo et al. (27) | 2019 | 22 | 17 | 39 | 56.41% | 0.564 | (0.408-0.720) | |
| Zhou et al. (28) | 2018 | 3 | 5 | 8 | 37.50% | 0.375 | (0.040-0.710) | ||
| Zhou et al. (21) | 2017 | 8 | 19 | 27 | 29.63% | 0.296 | (0.124-0.469) | ||
| Chen et al. (13) | 2016 | 14 | 37 | 51 | 27.45% | 0.275 | (0.152-0.397) | ||
| Yang et al. (22) | 2016 | 21 | 22 | 43 | 48.84% | 0.488 | (0.339-0.638) | ||
| Yang et al. (26) | 2016 | 16 | 19 | 35 | 45.71% | 0.457 | (0.292-0.622) | ||
| Hosgood et al. (14) | 2013 | 6 | 8 | 14 | 42.86% | 0.429 | (0.169-0.688) | ||
| Overall | 90 | 127 | 217 | 0.405 | (0.341-0.468) | ||||
| (Heterogeneity: I2 =48.0%, p=0.073) | |||||||||
| Uncommon mutation | Guo et al. (27) | 2019 | 17 | 22 | 39 | 43.59% | 0.436 | (0.280-0.592) | |
| Zhou et al. (28) | 2018 | 5 | 3 | 8 | 62.50% | 0.625 | (0.290-0.960) | ||
| Zhou et al. (21) | 2017 | 19 | 8 | 27 | 70.37% | 0.704 | (0.531-0.876) | ||
| Chen et al. (13) | 2016 | 37 | 14 | 51 | 72.55% | 0.725 | (0.603-0.848) | ||
| Yang et al. (22) | 2016 | 22 | 21 | 43 | 51.16% | 0.512 | (0.362-0.661) | ||
| Yang et al. (26) | 2016 | 19 | 16 | 35 | 54.29% | 0.543 | (0.378-0.708) | ||
| Hosgood et al. (14) | 2013 | 8 | 6 | 14 | 57.14% | 0.571 | (0.312-0.831) | ||
| Overall | 127 | 90 | 217 | 0.595 | (0.532-0.659) | ||||
| (Heterogeneity: I2 =48.0%, p=0.073) | |||||||||