Table 4.

DKD-related pathways from KEGG pathway analysis.

Downregulated/upregulated miRNAs	KEGG ID	Pathway	Count	p
Downregulated miRNAs	mmu04012	ErbB signaling pathway	15	<0.001
	mmu04010	MAPK signaling pathway	24	<0.01
	mmu04390	Hippo signaling pathway	16	<0.01
	mmu04310	Wnt signaling pathway	15	<0.01
	mmu04014	Ras signaling pathway	20	<0.01
	mmu04151	PI3K-Akt signaling pathway	26	<0.05
Upregulated miRNA	mmu04930	Type II diabetes mellitus	7	<0.001
	mmu04152	AMPK signaling pathway	7	<0.05
	mmu04066	HIF-1 signaling pathway	6	<0.05