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. 2020 Sep 22;8(11):e1500. doi: 10.1002/mgg3.1500

TABLE 4.

BRCA1/2 mutations frequencies in young women of Caucasians, African American, and Africans.

Study Mutation frequencies Sample size (n) Age limit Country
Africans
This study 10.0% 40 <35 years old Rwanda
Francies et al., (2015) 7.7% 78 <50 years old South Africa (Francies et al., 2015)
Fackenthal et al., (2012) 11.0% 265 <50 years old Nigeria (Ibadan; Fackenthal et al., 2012)
Tazzite et al., (2012) 12.5% 72 <50 years old Morocco (Tazzite et al., 2012)
Cherbal et al., (2010) 14.0% 49 ≤ 40 years old Algeria (Cherbal et al., 2010)
Troudi et al., (2007) 18.0% 36 ≤ 40 years old Tunisia (Troudi et al., 2007)
Awadelkarim et al., (2007) 12.0% 34 ≤ 40 years old Sudan (Awadelkarim et al., 2007)
Fackenthal et al., (2005) 2.5% 39 ≤ 40 years old Nigeria (Fackenthal et al., 2005)
Gao et al., (2000) 4.0% 70 ≤ 40 years old Nigeria (Gao et al., 2000)
Caucasians
Copson et al., (2018 ) 12.0% 2733 ≤ 40 years old UK (Copson et al., 2018)
de Sanjosé et al., (2003) 11.6% 136 ≤ 40 years old Spain (De Sanjosé et al., 2003)
Tonin et al., (2001) 13.0% 61 ≤ 40 years old Canada (Montreal; Tonin et al., 2001)
African American
Haffty et al. (2009) 14.0% 39 <45 years USA (New Jersey; Haffty et al., 2009)
John et al. (2007) 17.0% 30 <35 years old USA (North California; John, et al., 2007)
Malone et al., (2006) 10.3% 80 <45 years USA (Seattle; Malone et al., 2006)