Table 2.
List of multivesicular particles (DepoFoam) drugs along with their half-life and route of administration
| DepoFoam | Against | Subject | Administration | Half-life (h) | Reference | ||
|---|---|---|---|---|---|---|---|
| Drug | Active substance | Encapsulated | Unencapsulated | ||||
| DepoCyt | Cytarabine liposome | Lymphomatous meningitis | Human | Intrathecal | 82.4 | 3.4 | (29) |
| DepoDur | Morphine | Pain | Human | Epidural | 24-48 | 12-24 | (2) |
| DepoDFO | Desferrioxamine mesylate | Iron overload | Rat | Subcutaneous | 72 | 24 | (43) |
| EXPAREL | Liposomal Bupivacaine | Pain | Human | Subcutaneous | 96 | 24 | (3, 48) |
| Dog | Intravenous | 1.11 | 0.473 | (45) | |||
| Intra-arterial | 0.539 | 0.26 | |||||
| DepoIGF-I | Insulin-like growth factor I | Hormonal disorder | Rat | Subcutaneous | 26 | 4 | (17) |