Table 3.
Physical properties of propranolol HCl buccoadhesive tablets. Data are expressed as mean ± SD
| Formulation code | Thickness (mm) n = 10 |
Weight variation (g) n = 10 |
Hardness (Kp) n = 10 |
Friability (%) n = 20 |
|---|---|---|---|---|
| F1 | 2.41 ± 0.05 | 0.166 ± 0.004 | 7.13 ± 2.36 | 0.18 |
| F2 | 2.16 ± 0.04 | 0.157 ± 0.005 | 6.80 ± 2.9 | 0.80 |
| F3 | 2.16 ± 0.05 | 0.158 ± 0.004 | 6.43 ± 1.67 | 0.81 |
| F4 | 2.17 ± 0.12 | 0.161 ± 0.006 | 14.12 ± 1.59 | 0.18 |
| F5 | 2.03 ± 0.05 | 0.158 ± 0.004 | 10.93 ± 1.66 | 0.43 |
| F6 | 2.06 ± 0.07 | 0.162 ± 0.005 | 9.24 ± 1.85 | 0.24 |
| F7 | 2.26 ± 0.10 | 0.162 ± 0.004 | 8.70 ± 1.17 | 0.00 |
| F8 | 2.23 ± 0.06 | 0.160 ± 0.005 | 7.41 ± 1.15 | 0.22 |
| F9 | 2.19 ± 0.05 | 0163 ± 0.003 | 5.27 ± 1.17 | 0.34 |
| F10 | 2.19 ± 0.08 | 0.159 ± 0.005 | 4.59 ± 2.33 | 1.18 |
| F11 | 2.19 ± 0.14 | 0.163 ± 0.004 | 9.94 ± 1.69 | 0.49 |
| F12 | 2.19 ± 0.09 | 0.158 ± 0.004 | 11.37 ± 2.89 | 0.16 |
| F13 | 2.24 ± 0.09 | 0.159 ± 0.005 | 10.24 ± 0.70 | 0.75 |