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. 2020 Spring;19(2):182–186. doi: 10.22037/ijpr.2020.112583.13839

Table 2.

Antibacterial activity of phthalide derivatives 1-3

Compounds Staphylococcus aureus
Enterococcus faecium *
Escherichia coli
Pseudomonas aeruginosa
MIC (μg/mL)
1 256 >256 256 >256
2 128 256 128 >256
3 16 128 64 >256
Cefixime 2 16 4 64
Chloramphenicol 8 64 4 >256

*Vancomycin-resistant clinical strain