Table 2.
Antibacterial activity of phthalide derivatives 1-3
| Compounds |
Staphylococcus aureus
|
Enterococcus faecium
*
|
Escherichia coli
|
Pseudomonas aeruginosa
|
|---|---|---|---|---|
| MIC (μg/mL) | ||||
| 1 | 256 | >256 | 256 | >256 |
| 2 | 128 | 256 | 128 | >256 |
| 3 | 16 | 128 | 64 | >256 |
| Cefixime | 2 | 16 | 4 | 64 |
| Chloramphenicol | 8 | 64 | 4 | >256 |
*Vancomycin-resistant clinical strain