Table 3.
The single and combination effects of herbal samples with cisplatin on cell cycle phases
| Samples |
Sub G0
(% cell) |
G0/G1
(% cell) |
S
(% cell) |
G2/M
(% cell) |
|---|---|---|---|---|
| Negative control (RPMI) | 1.2 | 70.8 | 16.2 | 10.1 |
| Solvent | 2.8 | 68.3 | 14.4 | 11.5 |
| Cisplatin (2 µg/mL) | 16.9 | 52.2 | 9.8 | 18.1 |
| Cisplatin (10 µg/mL) | 30.4 | 45.9 | 6.3 | 14.9 |
| M. alba (crude) | 49.2 | 39.6 | 7.2 | 2.5 |
| M. alba (ethyl acetate) | 59.2 | 29.6 | 4.7 | 4.2 |
| M. alba (chloroformic) | 47.9 | 37.5 | 5.1 | 2.7 |
| Isoquercetin | 67.8 | 24.9 | 3.9 | 2.1 |
| Rutin | 40.1 | 41.2 | 9.8 | 6.3 |
| M. alba (crude) + Cisplatin (2 µg/mL) | 67.8 | 23.2 | 3.2 | 3.7 |
| M. alba (ethyl acetate) + Cisplatin (2 µg/mL) | 71.9 | 20.1 | 3.8 | 1.9 |
| M. alba (chloroformic) + Cisplatin (2 µg/mL) | 50.9 | 30.4 | 6.1 | 6.9 |
| Isoquercetin + Cisplatin (2 µg/mL) | 63.1 | 28.5 | 4.2 | 3.1 |
| Rutin + Cisplatin (2 µg/mL) | 40.1 | 40.8 | 9.1 | 7.1 |
| M. alba (crude) + Cisplatin (10 µg/mL) | 70.4 | 20.6 | 2.9 | 3.1 |
| M. alba (ethyl acetate) + Cisplatin (10 µg/mL) | 86.9 | 6.8 | 2.9 | 1.1 |
| M. alba (chloroformic) + Cisplatin (10 µg/mL) | 60.9 | 30.2 | 5.3 | 2.3 |
| Isoquercetin + Cisplatin (10 µg/mL) | 70.4 | 18.9 | 5.7 | 3.9 |
| Rutin + Cisplatin (10 µg/mL) | 52.1 | 32.7 | 6.0 | 5.2 |