Table 2.

The most significant DEGs scores in the treated AD mice with ibuprofen relative to the AD mice. Three are up-regulated while six are down-regulated. Tdo2 is the most down-regulated gene

Row	Gene Name	FC	P -value	Regulation
1	Penk	1.7	≤ 0.0007	Up
2	Dsp	1.9	≤ 0.0010	Down
3	Ecel1	1.6	≤ 0.0010	Up
4	Il1rl	1.5	≤ 0.0020	Down
5	Tdo2	2.5	≤ 0.0030	Down
6	zcchc5	1.6	≤ 0.0040	Down
7	Gm7120	1.7	≤ 0.0070	Down
8	snord115	1.4	≤ 0.0100	Up
9	Eif2s3y	1.4	≤ 0.0300	Down