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. 2020 Spring;19(2):352–359. doi: 10.22037/ijpr.2019.15485.13125

Table 3.

The list of central genes with high centrality values. Top 10% of genes based on degree, betweenness and closeness were considered and the genes that were common in the two centrality list were identified as central elements. K; degree, BC; Betweenness centrality, and CC; Closeness centrality. The asterisked genes are common between three groups of central nodes

Row Name Description K BC CC
1 Htr1a* 5-hydroxytryptamine (serotonin) receptor 1A 72 0.23 0.62
2 Sstr2* somatostatin receptor 2 70 0.10 0.59
3 Drd2* dopamine receptor D2 70 0.13 0.61
4 Htr1b* 5-hydroxytryptamine (serotonin) receptor 1B 70 0.10 0.60
5 Penk Preproenkephalin 69 0.00 0.59
6 Pomc pro-opiomelanocortin-alpha 69 0.00 0.59
7 Oprm1 opioid receptor, mu 1 69 0.00 0.59
8 Npy neuropeptide Y 69 0.00 0.59
9 Sst Somatostatin 69 0.00 0.59
10 Chrm2* cholinergic receptor, muscarinic 2 68 1.00 0.66