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. 2020 Spring;19(2):274–282. doi: 10.22037/ijpr.2019.111659.13292

Table 4.

Comparison of different method used for simultaneous determination of LIN and MET

Analyte Extraction technique Determnation technique Matrix LOD Ref.
LIN
MET
- RP-HPLC Pharmaceutical dosage 0.09 µgmL-1
0.06 µgmL-1
(24)
LIN
MET
- Spectrophotometric Pharmaceutical dosage 0.23 µgmL-1
0.77 µgmL-1
(26)
LIN
MET
- RP-HPLC Pharmaceutical dosage Not recorded
Not recorded
(28)
LIN
MET
NGO- DSPE RP-HPLC Plasma 2 ngmL-1
3 ngmL-1
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