Table 1.
Univariate and Multivariate Cox Regression Analyses of Clinicopathologic Characteristics Associated with Overall Survival in the Cancer Genome Atlas
| Variables | Univariate Analysis | Multivariate Analysis | ||
|---|---|---|---|---|
| HR (95% CI) | P-value | HR (95% CI) | P-value | |
| Age (>60/≤60) | 1.018 (0.995–1.041) | 0.125 | – | – |
| Gender (male/female) | 0.601 (0.345–1.048) | 0.073 | – | – |
| Grade (G4/G3/G2/G1) | 1.458 (0.997–2.133) | 0.878 | – | – |
| Stage (IV/III/II/I) | 1.595 (1.184–2.148) | 0.002a | 1.365 (0.511–3.645) | 0.535 |
| T stage (T4/T3/T2/T1) | 1.524 (1.134–2.047) | 0.005a | 1.143 (0.440–2.971) | 0.783 |
| Albumin (>3.5/≤3.5g/dL) | 0.964 (0.740–1.255) | 0.784 | – | – |
| Platelet (>250/≤250 × 109/L) | 0.999 (0.998–1.000) | 0.288 | – | – |
| AFP (> 20/≤ 20 ng/mL) | 1.000 (0.999–1.001) | 0.435 | – | – |
| Vascular invasion (macro/micro/none) | 1.920 (1.263–2.920) | 0.002a | 1.390 (1.850–2.275) | 0.189 |
| Risk score | 5.606 (3.466–9.068) | <0.001a | 4.989 (2.872–8.664) | <0.001a |
Note: aStatistically significant.
Abbreviations: AFP, alpha-fetoprotein; HR, hazard ratio; CI, confidence interval.