Table 2.
Univariate and Multivariate Cox Regression Analyses of Clinicopathologic Characteristics Associated with Overall Survival in the International Cancer Genome Consortium
| Variables | Univariate Analysis | Multivariate Analysis | ||
|---|---|---|---|---|
| HR (95% CI) | P - value | HR (95% CI) | P - value | |
| Age (>60/≤60) | 1.021 (0.985–1.057) | 0.255 | – | – |
| Gender (male/female) | 1.186 (0.538–2.617) | 0.673 | – | – |
| Hepatitis virus (none/infection) | 0.929 (0.360–2.394) | 0.878 | – | – |
| Stage (IV/III/II/I) | 1.373 (0.927–2.035) | 0.114 | – | – |
| Portal vein invasion (none/invasion) | 1.076 (0.694–1.671) | 0.741 | – | – |
| Vein invasion (none/invasion) | 2.243 (1.296–3.882) | 0.004a | 2.000 (0.835–4.801) | 0.120 |
| Bile duct invasion (none/invasion) | 0.481 (0.066–3.516) | 0.471 | - | - |
| Fibrosis (none/fibrosis) | 1.428 (0.195–10.439) | 0.726 | – | – |
| Risk score | 3.294 (3.601–10.770) | <0.001a | 3.243 (1.263–7.717) | 0.008a |
Note: aStatistically significant.
Abbreviations: HR, hazard ratio; CI, confidence interval.