Table 1. OP-NT Hybrid Peptides Designed and Investigated in the Present Studya.
compound number | sequence |
---|---|
3 | H-Dmt-d-Arg-Aba-β-Ala-Arg-Arg-Pro-Tyr-Tle-Leu-OH |
4 | H-Dmt-d-Arg-Aba-β-Ala-Lys-Lys-Pro-Tyr-Tle-Leu-OH |
5 | H-Dmt-d-Arg-Aba-β-Ala-Arg-Arg-Pro-Dmt-Tle-Leu-OH |
6 | H-Dmt-d-Arg-Aba-β-Ala-Lys-Lys-Pro-Dmt-Tle-Leu-OH |
7 | H-Dmt-d-Arg-Aba-β-Ala-β3hArg-Arg-Pro-Dmt-Tle-Leu-OH |
8 | H-Dmt-d-Arg-Aba-β-Ala-β3hLys-Lys-Pro-Dmt-Tle-Leu-OH |
9 | H-Dmt-d-Arg-Aba-β-Ala-Arg-Arg-Pro-(6-OH)Tic-Tle-Leu-OH |
10 | H-Dmt-d-Arg-Aba-β-Ala-Lys-Lys-Pro-(6-OH)Tic-Tle-Leu-OH |
11 | H-Dmt-d-Arg-Aba-β-Ala-Arg-Arg-Pro-m-Tyr-Tle-Leu-OH |
12 | H-Dmt-d-Arg-Aba-β-Ala-Lys-Lys-Pro-m-Tyr-Tle-Leu-OH |
All sequence modifications are highlighted in bold.