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. 2020 Sep 9;63(21):12929–12941. doi: 10.1021/acs.jmedchem.0c01376

Table 1. OP-NT Hybrid Peptides Designed and Investigated in the Present Studya.

compound number sequence
3 H-Dmt-d-Arg-Aba-β-Ala-Arg-Arg-Pro-Tyr-Tle-Leu-OH
4 H-Dmt-d-Arg-Aba-β-Ala-Lys-Lys-Pro-Tyr-Tle-Leu-OH
5 H-Dmt-d-Arg-Aba-β-Ala-Arg-Arg-Pro-Dmt-Tle-Leu-OH
6 H-Dmt-d-Arg-Aba-β-Ala-Lys-Lys-Pro-Dmt-Tle-Leu-OH
7 H-Dmt-d-Arg-Aba-β-Ala-β3hArg-Arg-Pro-Dmt-Tle-Leu-OH
8 H-Dmt-d-Arg-Aba-β-Ala-β3hLys-Lys-Pro-Dmt-Tle-Leu-OH
9 H-Dmt-d-Arg-Aba-β-Ala-Arg-Arg-Pro-(6-OH)Tic-Tle-Leu-OH
10 H-Dmt-d-Arg-Aba-β-Ala-Lys-Lys-Pro-(6-OH)Tic-Tle-Leu-OH
11 H-Dmt-d-Arg-Aba-β-Ala-Arg-Arg-Pro-m-Tyr-Tle-Leu-OH
12 H-Dmt-d-Arg-Aba-β-Ala-Lys-Lys-Pro-m-Tyr-Tle-Leu-OH
a

All sequence modifications are highlighted in bold.