Table 2.
Results of sensitivity analysis and subgroup analysis
| Categories | No. of studies |
Sensitivity (95% CI)/I2 |
Specificity (95% CI) /I2 |
AUC (95% CI) |
DOR (95% CI) |
PLR/NLR |
|---|---|---|---|---|---|---|
| Disease severity | ||||||
| Cut-off ≥ 4.5 | 6 | 0.74(0.66,0.80)/25.56 | 0.86(0.81,0.89)/36.40 | 0.86(0.83,0.89) | 17(10,28) | 5.1/0.31 |
| Cut-off < 4.5 | 7 | 0.82(0.71,0.89)/82.74 | 0.72(0.66,0.78)/79.70 | 0.82(0.78,0.85) | 12(7,19) | 3.0/0.25 |
| Published in English | 8 | 0.74(0.63,0.83)/73.82 | 0.78(0.71,0.84)/81.99 | 0.83(0.80,0.86) | 10(7,16) | 3.4/0.33 |
| Mortality | ||||||
| Cut-off ≥ 6.5 | 5 | 0.83(0.66,0.92)/84.97 | 0.87(0.77,0.93)/92.60 | 0.92(0.89,0.94) | 32(17,61) | 6.3/0.20 |
| Cut-off < 6.5 | 5 | 0.81(0.72,0.87)/0 | 0.77(0.64,0.86)/89.07 | 0.84(0.80,0.87) | 14(7,27) | 3.5/0.25 |
| Published in English | 6 | 0.83(0.69,0.91)/79.98 | 0.82(0.71,0.90)/89.87 | 0.90(0.87,0.92) | 23(12,41) | 4.7/0.21 |
AUC area under curve, PLR positive likelihood ratio, NLR negative likelihood ratio, DOR diagnostic odds ratio, CI credible interval