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. 2020 Aug 28;11(11):2087–2107. doi: 10.1021/acsmedchemlett.0c00202

Figure 1.

Figure 1

Late-occurring and long-circulating CYP-derived plasma metabolites of AZD7325 formed via metabolic cyclization and aromatization following repeat dosing in humans and preclinical animals. Adapted from Gu et al., 2018,5 under the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/).