Table 1.
Performance of different panel of candidate biomarkers in discovery cohort (74 AG and 68 NAG), validation cohort (set 1: 40 AG and 37 NAG; set 2: 40 AG and 13 NAG)
| Panel of candidate biomarkers | Area under the ROC curves (95% confidence interval) | ||
|---|---|---|---|
| Discovery cohort | Validation cohort | ||
| 40 AG and 37 NAG (set 1) | 40 AG and 13 NAG (set 2) | ||
| ACPP & Serum PSA | 0.82 (0.75,0.89) | 0.83 (0.74,0.92) | 0.8 (0.67,0.93) |
| ACPP & CLU & Serum PSA | 0.86 (0.8,0.92) | 0.85 (0.76,0.94) | 0.76 (0.6,0.92) |
| ACPP & LOX & Serum PSA | 0.82 (0.75,0.89) | 0.85 (0.76,0.93) | 0.81 (0.69,0.93) |
| ACPP & SERPINA1 & Serum PSA | 0.83 (0.76,0.9) | 0.84 (0.75,0.93) | 0.82 (0.7,0.94) |
| ACPP & ORM1 & Serum PSA | 0.83 (0.76,0.9) | 0.82 (0.72,0.91) | 0.82 (0.71,0.94) |