Table 2.

Results of Multivariable Cox regression analysis

Multivariable Cox Regression Analysis
Variables	Training cohort		Validation & Test cohort
	HR (95%CI)	P-value	HR (95%CI)	P-value
Risk score*	1.62 (1.24-2.11)	0.0004	1.40 (1.02-1.91)	0.04
Age (≥60 vs <60)	1.49 (1.24-1.80)	<0.0001	1.82 (1.35-2.46)	0.0001
Grade (High vs Low)	1.30 (1.06-1.60)	0.01	1.43 (1.04-1.98)	0.03
Stage (vs stage I)
II	1.27 (1.02-1.60)	0.03	1.98 (1.31-2.98)	0.001
III	2.86 (2.06-3.98)	<0.0001	2.80 (1.66-4.69)	0.0001
IV	3.40 (2.26-5.12)	<0.0001	5.25 (2.76-9.98)	<0.0001
Subtype (vs basal-like)
HER2	1.31 (0.99-1.74)	0.05	1.44 (0.97-2.14)	0.07
LumA	0.97 (0.73-1.30)	0.86	1.40 (0.88-2.23)	0.15
LumB	1.14 (0.88-1.49)	0.32	1.17 (0.79-1.73)	0.44
Normal like	1.19 (0.77-1.83)	0.43	1.17 (0.64-2.14)	0.60

*Continuous variable.