Table 2.

Pharmacokinetic parameters obtained after oral administration

	PLGNformulation IV	PPDP
AUC0-∞ (h·μg/mL) Cmax (μg/mL)	971.13±185.74* 61.04±15.38*	251.42±214.10 15.13±8.88
Tmax (hours)	5.00±0	5.00±1.00
t½ (hours)	10.40±2.85	15.28±3.00
Kel (hours)	0.07±0.01	0.05±0.01
MRT0–∞ (hours)	16.02±1.42	17.73±9.39

Notes: Each value represents the mean ± SD (n=6). *P<0.05 vs PPDP.

Abbreviations: PLGN, piroxicam-loaded gelatinnanocontainer; PPDP, piroxicam plain drug powder.