Table 2. Patient characteristics and sepsis-related organ involvement.
ARDS, acute respiratory distress syndrome; APACHE II, Acute Physiology and Chronic Health Evaluation II; AKI, acute kidney injury; AKIN, Acute Kidney Injury Network; CNS, central nervous system; ICU, intensive care unit; IQR, interquartile range; MAP, mean arterial pressure, RRT, renal replacement therapy; SOFA, Sequential Organ Failure Assessment
| Characteristics median (IQR) | All patients (n = 163) | Survivors (n = 95) | Non-survivors (n = 68) | p-Values |
| SOFA | 8 (6-10) | 8 (5-10) | 9 (7-1) | 0.03 |
| APACHE II | 17 (13-22) | 15 (12-20) | 20 (16-27) | <0.001 |
| Mechanically ventilated (%) | 137 (84) | 73 (77) | 64 (94) | <0.001 |
| Base excess | -9 (-12 to -5) | -8 (-11 to -5) | -11 (-13 to -6) | <0.001 |
| AKI (any stage), n (%) | 115 (71) | 53 (56) | 62 (91) | <0.001 |
| AKIN stage 1 | 7 (4.3) | 3 (3) | 4 (6) | 0.45 |
| AKIN stage 2 | 31 (19) | 15 (15.8) | 16 (24) | 0.23 |
| AKIN stage 3 | 77 (47) | 35 (37) | 42 (62) | <0.001 |
| RRT (%) | 48 (30) | 23 (48) | 25 (52) | 0.08 |
| Moderate-to-severe ARDS (%) | 74 (45) | 32 (43) | 42 (57) | <0.001 |
| Septic shock (%) | 119 (73) | 63 (66) | 56 (82) | 0.03 |
| MAP < 60 mmHg (%) | 12 (7.4) | 2 (2) | 10 (15) | 0.00 |
| Days on ventilator | 4 (1-8) | 4 (1-7) | 5 (2-11) | 0.02 |
| ICU days | 6 (3-11) | 6 (4-10) | 6 (3-13) | 0.96 |
| Suspected source (%) | ||||
| Lungs | 54 (33) | 34 (36) | 20 (29) | 0.40 |
| Urological | 23 (14) | 19 (20) | 4 (6) | 0.01 |
| Abdomen | 27 (17) | 10 (11) | 17 (25) | 0.02 |
| Pancreas | 10 (6) | 6 (6) | 4 (6) | 1.00 |
| CNS | 6 (4) | 2 (2) | 4 (6) | 0.23 |
| Skin/soft tissue | 9 (5) | 5 (5) | 4 (6) | 1.00 |
| Surgical site | 5 (3) | 1 (1) | 4 (6) | 0.16 |
| Other/unknown | 29 (18) | 18 (19) | 11 (16) | 0.68 |