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. Author manuscript; available in PMC: 2020 Nov 16.
Published in final edited form as: Nat Immunol. 2020 Jan 20;21(2):221–231. doi: 10.1038/s41590-019-0582-z

Figure 2: Strain-specific transcriptomes of lung mononuclear phagocytes (MPs) at baseline.

Figure 2:

a. Comparison of gene expression in B6 and DBA mice for each lung MP subset. Scatter plots are showing genes with transcripts per million (TPM) > 4. Pale blue dots show genes with fold change (FC) 2 or higher, dark blue dots show genes with FC 4 or higher. N=2 for each cell type in both strains.

b. Inter-cellular and inter-strain comparison of highly differentially expressed genes. Heat map shows unsupervised hierarchical clustering of genes with FC 4 or higher between the strains. Values are row z-score.

c. Examples of strain specific genes included in the heat map in Fig. 2b. Bar graphs represent mean log2 transcripts per million (TPM+1) ± SD, N=2. Asterisks indicate statistical significance, * p-adj < 0.05, ** p-adj < 0.01, *** p-adj < 0.001 calculated by DESeq2 and multiple-testing corrected with Benjamini-Hochberg.