Table 2.
Data for the CSF sterility at the 10 weeks follow-up
| Group I (AmB+ | Group II (AmB + | P-value | |
|---|---|---|---|
| Fluconazole+ 5-FC,n = 27) | Fluconazole+ 5-FC + VPS, na = 38) | ||
| case (n, %) | 8 (29.6%) | 22 (56.4%) | 0.033* |
| Daysb (mean ± SD) | 29.2 ± 20.0 | 32.5 ± 24.8 | 0.909 |
| ≤ 2 weeks (n, %) | 2 (7.4%) | 8 (20.5%) | 0.662 |
| > 2 weeks (n, %) | 6 (22.2%) | 14 (35.9%) | |
| ≤ 4 weeks (n, %) | 4 (14.8%) | 13 (33.3%) | 0.730 |
| > 4 weeks (n, %) | 4 (14.8%) | 9 (23.1%) |
AmB amphotericin B, 5-Fc flucytosine, Flu fluconazole, SD standard deviation. Continuous variables analyzed by t-test; categorical variables analyzed by chi-square test or Fisher’s exact test
a One patient was lost to -follow-up at the 10th week in Group II
b‘Days’ indicates the time from diagnosis to the first negative CSF india ink stain
*P < 0.05