Table 4.
Results for mortality
| Author | Journal | Year | Number | Age (years) | Result |
|---|---|---|---|---|---|
| Difference | |||||
| Murphy [14] | Bone Joint J | 2018 | 2838 |
< 80, ≥ 80 |
Mortality hazard ratio in ≥ 80-years group is 3.40 (2.54–4.54, P < 0.001) |
| Skinner [37] | Ann R Coll Surg Eng | 2016 | 67 |
70–79, 90–99 |
Mortality rates were higher in the nonagenarian group but these were in keeping with the life expectancy projections identified by the Office for National Statistics |
| Shah [20] | J knee Surg | 2016 | 33,066 |
< 65, ≥ 65 |
Young cohort had lower rate of mortality (0.03 vs. 0.18%, P < 0.001) |
| Jauregui [39] | J Arthroplast | 2015 | 35,342 |
< 90, ≥ 90 |
Serious postoperative adverse events that were significantly higher in nonagenarians compared to controls included death (0.9% vs. 0.2%; P = 0.024) |
| Maempel [40] | Acta Orthop | 2015 | 3144 |
< 75, 75–80, > 80 |
Odds ratios for mortality at 1 year, adjusted for ASA, were 2.2 (1.0–4.5) for age 75–80, and 3.0 (1.3–6.8) for age > 80, relative to age < 75 years |
| Belmont [42] | J Bone Joint Surg Am | 2014 | 15,321 | Patient age (OR = 1.12; 95% CI, 1.06 to 1.17) was independent predictor of mortality | |
| D’Apuzzo [43] | J Arthroplast | 2014 | 5,492,805 |
< 90, ≥ 90 |
In-hospital mortality was significantly higher in the older cohort compared to the younger group (2.9% versus 0.2%; P < 0.001) |
| Easterlin [46] | Clin Orthop Rel Res | 2013 | 8950 |
40–64, 65–69, 70–74, 75–79, 80–84, 85–89 |
Age was associated with increased risk of mortality starting at age 85 years; mortality in patients 85 years and older was 17 times higher than in those younger than 65 years (OR: 70–74 (1.21), 75–79 (2.85), 80–84 (2.57), 85–89 (17.65) |
| Kennedy [48] | Clin Orthop Rel Res | 2013 |
≥ 80: 438 < 80: 2754 |
< 80, ≥ 80 |
Octogenarians had a higher (P < 0.001) mortality rate in Kaplan-Meier survival analysis |
| Jämsen [51] | Acta Orthop | 2012 | 1998 |
75–79, 80–84, ≥ 85 |
Adjusted hazard ratio for age 75–79 years is 1, for 80–84 years it is 1.71 [1.31–2.23], for 85 years or over it is 3.34 (2.39–4.65) |
| Singh [52] | J Arthroplast | 2012 | 12,484 | Older age was associated with higher 90-day all-cause mortality. OR for age (per 5-year increase) is 1.6 (1.3–1.9) in univariate analysis and 1.6 (1.2–1.7) in multivariable-adjusted analysis | |
| Kreder [59] | J Arthroplast | 2005 | 15,029 |
65–79, > 80 |
Patients > 80 years of age are 3.4 times more likely to die |
| No difference | |||||
| Kuo [44] | J Orthop Surg Res | 2014 | 1024 |
< 80, ≥ 80 |
There was no 90-day mortality in either group |
| Robertsson [58] | Bone Joint J | 2007 | 57,979 |
< 54, 55–59, 60–64, 65–69, 70–74, 75–79, 80–84, > 85 |
Patients younger than 55 years had a statistically significant increase in total mortality (standardized mortality ratio: 1.85 [1.53–2.22]) while patients older than 65 years had a statistically significant decrease |
OR odds ratio