Table 2.
Hazard ratios along with their 95% confidence intervals for the 12 most influential variables for the Cox models. Variables are presented in decreasing order according to the absolute z-score values (12.90 to 5.16) for the Cox model with all variables. Predictors shown are the most prognostic as their z-scores values correspond to low and very significant p-values. These variables were also selected by both Cox backward and Cox LASSO model which verifies their prognostic ability for Cox models
Cox all variables | Cox backward | Cox LASSO | |
---|---|---|---|
HR (95% CI) | HR (95% CI) | HR | |
Re-transplantation | 1.602 (1.491-1.721) | 1.608 (1.501-1.722) | 1.558 |
Donor age | 1.010 (1.008-1.011) | 1.011 (1.009-1.012) | 1.009 |
Donor type DCD (a) | 1.483 (1.362-1.616) | 1.443 (1.338-1.556) | 1.298 |
log(Total cold ischemic time) | 1.258 (1.192-1.327) | 1.285 (1.221-1.353) | 1.191 |
Diabetes | 1.173 (1.125-1.225) | 1.176 (1.128-1.226) | 1.136 |
Race Black (b) | 1.240 (1.171, 1.314) | 1.261 (1.193-1.332) | 1.186 |
Life support | 1.343 (1.240-1.454) | 1.375 (1.272-1.487) | 1.304 |
Recipient age | 1.007 (1.005-1.009) | 1.008 (1.006-1.010) | 1.006 |
Incidental tumour | 1.314 (1.202, 1.437) | 1.315 (1.203-1.437) | 1.203 |
Hypertensive bleeding | 1.296 (1.185, 1.418) | 1.301 (1.190-1.423) | 1.214 |
HCV (c) serology status | 1.147 (1.091-1.206) | 1.148 (1.094-1.205) | 1.166 |
Pre-treatment status ICU (d) | 1.240 (1.143, 1.346) | 1.253 (1.160-1.354) | 1.164 |
(a): Donor type DCD (Donor Circulatory Dead) vs DBD (Donor after Brain-Dead), (b): Race Black vs White, (c): Chronic hepatitis C virus, (d): Intense Care Unit vs Non-hospitalised/Hospitalised